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Understanding the Anti-CCP Blood Test

The Anti-CCP (Cyclic Citrullinated Peptide) blood test is a serological test used to detect and measure Rheumatoid Arthritis(RA). This is an autoimmune condition that causes chronic inflammation of the joints and can lead to severe joint damage if not detected and treated early.

Anti-CCP antibodies are highly specific for RA and their presence typically antedates clinical features. The test is usually ordered along with other markers of inflammation to make a diagnosis and forecast the prognosis of the disease.

Anti-CCP Blood Test Measures

The Anti-CCP Blood Test measures the blood concentration of anti-cyclic citrullinated peptide antibodies. The auto-antibodies target proteins that have been citrullinated, a biochemical process that is frequently associated with auto-immune activity in rheumatoid arthritis. The results typically are expressed in units per milliliter (U/mL) and are graded as negative, weakly positive, or strongly positive.

 

Parameter

Details

Test Name

Anti-CCP Blood Test

Full Form

Anti-Cyclic Citrullinated Peptide Antibody Test

What It Measures

Concentration of anti-CCP antibodies in the blood

Target Molecule

Proteins that undergo citrullination (commonly linked to autoimmune activity in RA)

Units of Measurement

Units per milliliter (U/mL)

Typical Result Categories

- Negative: < 20 U/mL - Weak Positive: 20–39 U/mL - Strong Positive: ≥ 40 U/mL

Clinical Relevance

Early and specific detection of rheumatoid arthritis, especially in RF-negative cases

Anti-CCP Blood Test Price For Other Cities

What is an Anti-CCP Blood Test?

The Anti-CCP test is utilized in the detection of antibodies to cyclic citrullinated peptides. These are specifically specific to rheumatoid arthritis and are typically present in the blood years before the onset of clinical symptoms. The test is specifically useful in the detection of seronegative RA, when RF assay is negative.

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Frequently Asked Questions

What conditions does the Anti-CCP test detect?

What is the normal range for Anti-CCP antibodies?

What is the difference between Anti-CCP and Rheumatoid Factor (RF)?

Is the Anti-CCP test accurate for diagnosing rheumatoid arthritis (RA)?

Can I take this test if I have joint pain but no RA diagnosis yet?

Can the Anti-CCP test predict future joint damage or RA progression?

Do I need to fast before the Anti-CCP test?

Is the Anti-CCP test part of any arthritis or autoimmune panel?

Can I take the Anti-CCP test while on arthritis medication?

What does a positive Anti-CCP test result mean?

Can I book an Anti-CCP test at home with MAX@Home?

How soon will I receive my Anti-CCP test reports from MAX@Home?

How much does the Anti-CCP Blood Test cost with MAX@Home?

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Dr. SANA ABEDIN
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Last Updated :
September 22, 2025

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