Quantiferon TB-Gold

What is the QuantiFERON-TB Gold Test?

The QuantiFERON-TB Gold Test is a blood test used to detect tuberculosis (TB) infection by measuring the body’s immune response to TB-specific antigens. It is also known as an Interferon-Gamma Release Assay (IGRA) and is considered more accurate and convenient than the traditional tuberculin skin test (TST). This test works by detecting the release of interferon-gamma (IFN-γ) from white blood cells when exposed to TB antigens. It is used to identify both latent TB infection and active TB disease, although additional tests may be needed to confirm active disease.

Importance of the QuantiFERON-TB Gold Test

The QuantiFERON-TB Gold Test plays a significant role in the early detection and control of tuberculosis. It offers a more reliable alternative to the traditional tuberculin skin test, especially in BCG-vaccinated populations like India, where false positives are common with older testing methods.

Key Benefits of the Test:

• Higher Specificity: Accurately detects TB infection without being influenced by prior BCG vaccination.
• Single Visit Requirement: Unlike skin tests that need a follow-up visit for result interpretation, this blood test requires only one sample collection.
• Objective Results: Lab-based analysis ensures standardised and unbiased interpretation.
• Useful for High-Risk Groups: Ideal for healthcare workers, immunocompromised individuals, and those in contact with TB patients.

Early screening with the QuantiFERON-TB Gold Test helps reduce transmission and allows for timely treatment, especially in asymptomatic or latent TB cases.

Who Should Get the QuantiFERON-TB Gold Test?

The QuantiFERON-TB Gold Test is recommended for individuals who are at risk of tuberculosis infection, especially in environments where exposure is more likely or where accurate screening is essential for public health.

This test is suitable for:

• People who have been in close contact with someone diagnosed with TB
• Healthcare workers and caregivers regularly exposed to patients
• Individuals with weakened immune systems, such as those with HIV, diabetes, or undergoing immunosuppressive treatment
• People with TB-like symptoms who need confirmatory testing
• Individuals with a history of TB exposure or who have lived in TB-endemic areas
• Candidates for TB screening before employment, surgery, or migration

Consulting a healthcare provider can help determine whether this test is appropriate based on symptoms, exposure history, or clinical need.

Symptoms That May Require TB Testing

Tuberculosis can develop gradually, and its symptoms may often be mistaken for other common illnesses. Identifying and testing for TB early, especially in the presence of persistent or unexplained symptoms, can help prevent complications and limit transmission. Common symptoms that may indicate the need for TB testing include:

• Cough lasting more than two weeks
• Unexplained weight loss
• Fever or persistent low-grade fever
• Night sweats
• Fatigue or weakness
• Loss of appetite
• Chest pain or discomfort when breathing or coughing

QuantiFERON-TB Gold Test Procedure and Sample Collection

The QuantiFERON-TB Gold Test is a straightforward and minimally invasive blood test that can be easily done at home with professional assistance from MaxAtHome.

How the Test is Performed

A trained phlebotomist collects a small blood sample from a vein in the arm using a sterile needle. The sample is then transported under controlled conditions to a certified laboratory for analysis, where it is tested for interferon-gamma response to TB-specific antigens.

Home Sample Collection with MaxAtHome

MaxAtHome ensures a smooth and safe sample collection process by offering:

• Free home sample collection at a time convenient for you
• Certified professionals trained in hygiene and safe handling
• No need to visit a clinic, making it especially beneficial for individuals with busy schedules or mobility concerns

The entire process takes just a few minutes, and the sample is processed quickly to deliver accurate results.

Fasting Requirements and Report Availability

Before undergoing any lab test, it's natural to ask about preparation and how soon results will be available. Here's what to expect with the QuantiFERON-TB Gold Test.

Is Fasting Required?

No, fasting is not required for the QuantiFERON-TB Gold Test. Individuals can eat and drink as usual unless specifically instructed otherwise by a healthcare provider.

Report Availability

MaxAtHome ensures timely delivery of results to support prompt medical follow-up:

• Digital reports are available within 2 days of sample collection
• Reports can be securely accessed through the MaxAtHome website or app
• In case of a positive or indeterminate result, follow-up with a doctor is recommended for further evaluation

Understanding Your QuantiFERON-TB Gold Test Results

The QuantiFERON-TB Gold Test provides an indication of whether a person’s immune system has reacted to TB-specific antigens, suggesting exposure to tuberculosis bacteria. However, it does not distinguish between latent TB infection and active TB disease—further evaluation may be required for a complete diagnosis.

What the Results May Indicate:

• Positive: TB infection is likely. Additional tests (such as a chest X-ray or sputum test) may be needed to confirm active TB.
• Negative: TB infection is unlikely, though results should be interpreted in context with symptoms and exposure history.
• Indeterminate: The test result was inconclusive. This may occur due to issues with the sample or immune response. Retesting may be recommended.

Your healthcare provider will use these results alongside clinical symptoms and medical history to determine the appropriate next steps.

Cost and Availability of the QuantiFERON-TB Gold Test

MaxAtHome offers the QuantiFERON-TB Gold Test as a safe, accessible, and home-based option for TB screening, making it convenient for individuals across different cities in India.

Factors Affecting the Price of Home Testing

The cost of the test may vary depending on:

• The city or region where the test is booked
• Whether the test is taken alone or as part of a larger diagnostic panel
• Applicable home collection charges (MaxAtHome offers free sample collection)
• Any ongoing discounts or promotional offers

Despite these factors, MaxAtHome ensures transparent pricing with no hidden costs, providing a seamless experience for those seeking reliable TB testing.

How to Book the QuantiFERON-TB Gold Test with MaxAtHome

Booking the QuantiFERON-TB Gold Test with MaxAtHome is quick, convenient, and designed to prioritise your comfort, especially when testing for an infection like TB.

Follow these simple steps to get started:

• Schedule the test online through our easy-to-use booking platform.
• Select your city and preferred time slot for home sample collection.
• Enter your details and confirm the appointment in just a few clicks.
• A trained phlebotomist will visit your home at the scheduled time for sample collection.
• Receive your digital report within 2 days, directly via the MaxAtHome website or app.

For any queries or booking support, call 01244781023 to speak with our customer care team.